{"id":412,"date":"2023-07-13T12:44:00","date_gmt":"2023-07-13T10:44:00","guid":{"rendered":"https:\/\/staging-scf.agence-nsw.xyz\/chemobiologie\/actualites\/prix-de-these\/"},"modified":"2023-07-13T12:44:00","modified_gmt":"2023-07-13T10:44:00","slug":"prix-de-these","status":"publish","type":"post","link":"https:\/\/staging-scf.agence-nsw.xyz\/chemobiologie\/fr\/actualites\/prix-de-these\/","title":{"rendered":"Prix de th\u00e8se"},"content":{"rendered":"\n<h2 class=\"has-text-align-center wp-block-heading\">\u00c9dition 2025<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">SCF-ChemBio attribue chaque ann\u00e9e un <strong><span class=\"has-inline-color has-vivid-cyan-blue-color\">Prix de th\u00e8se.<\/span><\/strong> L\u2019objectif est de r\u00e9compenser des travaux de th\u00e8se innovants et\/ou \u00e0 fort impact dans le domaine de la ch\u00e9mobiologie. <br> <br>Le\/la laur\u00e9at(e) de ce prix de th\u00e8se SCF-ChemBio aura l\u2019opportunit\u00e9 de faire une communication orale lors du congr\u00e8s national de la SCF qui aura lieu \u00e0 Bordeaux en juin 2026. Il\/elle sera \u00e9galement exon\u00e9r\u00e9(e) des frais d\u2019inscription \u00e0 ce congr\u00e8s.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Plus d&rsquo;information pour postuler au Prix de th\u00e8se 2025 de la division transversale de Ch\u00e9mobiologie : chimie et vivant de la SCF (SCF-ChemBio) sont disponibles dans le document ci-dessous.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>More info to apply for PhD award 2026 of the chemical biology transversal division of the SCF (SCF-ChemBio) can be found here:<\/em><\/p>\n\n\n\n<div class=\"wp-block-file\"><a href=\"https:\/\/new.societechimiquedefrance.fr\/wp-content\/uploads\/2025\/11\/Candidature-Prix-These-SCF-ChemBio-2025_Final.docx\">Candidature-Prix-These-SCF-ChemBio-2025_Final<\/a><a href=\"https:\/\/new.societechimiquedefrance.fr\/wp-content\/uploads\/2025\/11\/Candidature-Prix-These-SCF-ChemBio-2025_Final.docx\" class=\"wp-block-file__button\" download>T\u00e9l\u00e9charger<\/a><\/div>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\"><\/p>\n\n\n\n<h2 class=\"has-text-align-center wp-block-heading\">\u00c9dition 2025<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"block-1ef92ce2-0719-4c12-8e5f-20d4a08659a5\">Le prix de th\u00e8se 2025 a \u00e9t\u00e9 attribu\u00e9 \u00e0&nbsp;<strong>Laurane Michel<\/strong>, qui a effectu\u00e9 son doctorat <a href=\"https:\/\/lbm.cnrs.fr\/\">\u00e0 l\u2019<\/a><a href=\"https:\/\/icsn.cnrs.fr\/\">Institut de Chimie des Substances Naturelles <\/a><a href=\"https:\/\/lbm.cnrs.fr\/\">(CNRS-UPR 2301, Universit\u00e9 Paris-Saclay)<\/a> sous la supervision du Dr Arnaud Chevalier.<\/p>\n\n\n\n<figure class=\"wp-block-image is-resized\" id=\"block-a322d09e-36d1-4533-8673-6f9944af91be\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/new.societechimiquedefrance.fr\/wp-content\/uploads\/2026\/02\/JCJC-winenr-768x1024.jpg\" alt=\"Cette image a un attribut alt vide\u00a0; le nom du fichier est JCJC-winenr-768x1024.jpg\" width=\"285\" height=\"380\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\" id=\"block-665ceb41-849f-4bd6-b8c8-8bbff8afdc65\">Apres 2 ans de classes pr\u00e9paratoire CPGE, Laurane Michel a obtenu son dipl\u00f4me d&rsquo;ing\u00e9nieur en Chimie avec une sp\u00e9cialit\u00e9 en Chimie Organique \u00e0 l&rsquo;Universit\u00e9 de Strasbourg en 2021. Parall\u00e8lement, elle a obtenu un Master en Chimie Mol\u00e9culaire et Supramol\u00e9culaire. Son grand int\u00e9r\u00eat pour les projets interdisciplinaires l&rsquo;a conduit \u00e0 r\u00e9aliser son doctorat \u00e0 l\u2019Institut de Chimie des Substances Naturelles (CNRS-UPR 2301, Universit\u00e9 Paris-Saclay) sous la supervision du Dr Arnaud Chevalier. Son projet de th\u00e8se a port\u00e9 sur la g\u00e9n\u00e9ration de nouvelles strat\u00e9gies th\u00e9rapeutiques pour impacter les fonctions mitochondriales. Elle a notamment travaill\u00e9 sur la synth\u00e8se de sondes fluorog\u00e9niques permettant la visualisation d\u2019une activit\u00e9 azor\u00e9ductase intramitochondriale en condition de normoxie. Elle a ensuite synth\u00e9tis\u00e9 et \u00e9valu\u00e9 plusieurs plateformes chimiques tripartites mito-cibl\u00e9es activables enzymatiquement par des activit\u00e9s r\u00e9ductases mitochondriales afin de permettre la lib\u00e9ration intra-mitochondriale de mol\u00e9cules neutres, dans le but ultime de permettre le transport de principes actifs puis leur lib\u00e9ration s\u00e9lective \u00e0 l&rsquo;int\u00e9rieur de la mitochondrie. Enfin, elle a abord\u00e9 la synth\u00e8se d\u2019une nouvelle biblioth\u00e8que de photosensibilisants mito-cibl\u00e9es pour une utilisation en th\u00e9rapie photodynamique. Depuis avril 2025, elle r\u00e9alise un post-doctorat en Suisse \u00e0 l&rsquo;Universit\u00e9 de Gen\u00e8ve, dans l&rsquo;\u00e9quipe du Prof. Sascha Hoogendoorn, sur la synth\u00e8se et l&rsquo;\u00e9valuation biologique de PROTACs photoprot\u00e9g\u00e9s afin de comprendre le fonctionnement de la voie Hedgehog dans les cils cellulaires.<\/p>\n\n\n\n<h2 class=\"has-text-align-center wp-block-heading\">\u00c9dition 2024<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Le prix de th\u00e8se 2024 a \u00e9t\u00e9 attribu\u00e9 \u00e0, <span class=\"has-inline-color has-vivid-cyan-blue-color\"><strong>Lina El Hajji<\/strong><\/span>, qui a effectu\u00e9 son doctorat au sein du <a href=\"https:\/\/lbm.cnrs.fr\/\">laboratoire des Biomol\u00e9cules<\/a> (UMR7203, Sorbonne Universit\u00e9, ENS-PSL, CNRS).<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/new.societechimiquedefrance.fr\/wp-content\/uploads\/2023\/07\/Lina.jpg\" alt=\"\" class=\"wp-image-214248\" width=\"273\" height=\"299\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Apr\u00e8s deux ann\u00e9es de CPGE \u00e0 Nancy, Lina El Hajji a int\u00e9gr\u00e9 le d\u00e9partement de chimie de l\u2019\u00e9cole Normale Sup\u00e9rieure de Paris o\u00f9 elle a obtenu une licence de chimie en 2018 puis un Master en chimie et sciences du vivant en 2020. Elle a effectu\u00e9 son stage de Master 2 puis son doctorat sous la direction du Prof. Arnaud Gautier au laboratoire des Biomol\u00e9cules (UMR7203, Sorbonne Universit\u00e9, ENS-PSL, CNRS). Sa th\u00e8se a port\u00e9 sur l\u2019ing\u00e9nierie de rapporteurs fluorescents chimiog\u00e9n\u00e9tiques fluorescents pour l\u2019imagerie et le multiplexage. En utilisant une strat\u00e9gie concert\u00e9e d\u2019ing\u00e9nierie mol\u00e9culaire et d\u2019\u00e9volution dirig\u00e9e, elle a d\u00e9velopp\u00e9 un rapporteur chimiog\u00e9n\u00e9tique fluorescent dans le proche infrarouge pour l\u2019imagerie multicouleur en cellules et en organismes vivants et l\u2019induction de proximit\u00e9 entre prot\u00e9ines. Elle a \u00e9galement d\u00e9velopp\u00e9 des rapporteurs chimiog\u00e9n\u00e9tiques compatibles avec le multiplexage en temps de vie de fluorescence. Lina est actuellement en stage post-doctoral dans l\u2019\u00e9quipe Chimiog\u00e9n\u00e9tique pour l\u2019imagerie et le contr\u00f4le des fonctions cellulaires co-affili\u00e9e au laboratoire Chimie Physique et Chimie du vivant (UMR8228 SU\/ENS-PSL\/CNRS) et au laboratoire Chemical Biology of Cancer (Institut Curie UMR3666\/U1339) o\u00f9 elle d\u00e9veloppe des int\u00e9grateurs fluorescents capables d\u2019enregistrer une activit\u00e9 cellulaire.<\/p>\n\n\n\n<h2 class=\"has-text-align-center wp-block-heading\">\u00c9dition 2023<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Le prix de th\u00e8se 2023 a \u00e9t\u00e9 attribu\u00e9 \u00e0 <strong><span class=\"has-inline-color has-vivid-cyan-blue-color\">S\u00e9bastien Depienne<\/span><\/strong> qui a effectu\u00e9 son doctorat au sein du <a href=\"https:\/\/ceisam.univ-nantes.fr\/\"><em><span class=\"has-inline-color has-vivid-cyan-blue-color\">laboratoire Chimie Et Interdisciplinarit\u00e9, Synth\u00e8se, Analyse, Mod\u00e9lisation (CEISAM<\/span><\/em>)<\/a> &#8211; UMR6230 \u00e0 Nantes<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/new.societechimiquedefrance.fr\/wp-content\/uploads\/2024\/01\/Sebastien-Depienne.jpg\" alt=\"\" class=\"wp-image-199356\" width=\"208\" height=\"267\" \/><\/figure><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>S\u00e9bastien Depienne<\/strong> a effectu\u00e9 ses \u00e9tudes sup\u00e9rieures \u00e0 Nantes Universit\u00e9 (Nantes, France) o\u00f9 il a obtenu une licence de chimie en 2017 puis un master de chimie organique (Chimie Mol\u00e9culaire Th\u00e9rapeutique) en 2019. Il a ensuite r\u00e9alis\u00e9 une th\u00e8se de doctorat au laboratoire CEISAM (UMR6230, CNRS-Nantes Universit\u00e9) sous la direction des Dr S\u00e9bastien Gouin et Dr Mohammed Boujtita. Ses travaux de th\u00e8se ont concern\u00e9 l\u2019optimisation et le d\u00e9veloppement de la premi\u00e8re m\u00e9thodologie de bioconjugaison de prot\u00e9ines sous activation \u00e9lectrochimique, en ciblant l\u2019acide amin\u00e9 tyrosine. Apr\u00e8s avoir identifi\u00e9 un syst\u00e8me r\u00e9actionnel biocompatible, rapide et rigoureusement tyrosine-s\u00e9lectif, l\u2019efficacit\u00e9 de la strat\u00e9gie <em>click-electrochemistry <\/em>a pu \u00eatre illustr\u00e9e \u00e0 l\u2019\u00e9chelle de peptides, enzymes et anticorps de pertinence th\u00e9rapeutique. Ensuite, la possibilit\u00e9 d\u2019\u00e9lectro-fonctionnaliser directement les surfaces complexes de virus, bact\u00e9ries et cellules eucaryotes a \u00e9t\u00e9 explor\u00e9e et a cela a pu \u00eatre d\u00e9montr\u00e9 avec des motifs biopertinents et bioorthogonaux, de fa\u00e7on reproductible, biocompatible et notablement rapide. S\u00e9bastien est \u00e0 pr\u00e9sent chercheur postdoctoral dans le groupe du Prof. Bruno Linclau (Ghent University, Belgique) o\u00f9 il pr\u00e9pare et \u00e9tudie des d\u00e9riv\u00e9s glycosidiques polyfluor\u00e9s lipophiles pour des applications en glycobiologie et glycomim\u00e9tiques.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c9dition 2025 SCF-ChemBio attribue chaque ann\u00e9e un Prix de th\u00e8se. L\u2019objectif est de r\u00e9compenser des travaux de th\u00e8se innovants et\/ou \u00e0 fort impact dans le domaine de la ch\u00e9mobiologie. Le\/la laur\u00e9at(e) de ce prix de th\u00e8se SCF-ChemBio aura l\u2019opportunit\u00e9 de faire une communication orale lors du congr\u00e8s national de la SCF qui aura lieu \u00e0 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-412","post","type-post","status-publish","format-standard","hentry","category-actualites"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prix de th\u00e8se - SCF Division Ch\u00e9mobiologie<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Prix de th\u00e8se - SCF Division Ch\u00e9mobiologie\" \/>\n<meta property=\"og:description\" content=\"\u00c9dition 2025 SCF-ChemBio attribue chaque ann\u00e9e un Prix de th\u00e8se. L\u2019objectif est de r\u00e9compenser des travaux de th\u00e8se innovants et\/ou \u00e0 fort impact dans le domaine de la ch\u00e9mobiologie. Le\/la laur\u00e9at(e) de ce prix de th\u00e8se SCF-ChemBio aura l\u2019opportunit\u00e9 de faire une communication orale lors du congr\u00e8s national de la SCF qui aura lieu \u00e0 [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/staging-scf.agence-nsw.xyz\/chemobiologie\/fr\/actualites\/prix-de-these\/\" \/>\n<meta property=\"og:site_name\" content=\"SCF Division Ch\u00e9mobiologie\" \/>\n<meta property=\"article:published_time\" content=\"2023-07-13T10:44:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/new.societechimiquedefrance.fr\/wp-content\/uploads\/2026\/02\/JCJC-winenr-768x1024.jpg\" \/>\n<meta name=\"author\" content=\"comscf\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"comscf\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/\"},\"author\":{\"name\":\"comscf\",\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/#\\\/schema\\\/person\\\/fc6f4a6ec9b19ccf4ca85a485a1145c0\"},\"headline\":\"Prix de th\u00e8se\",\"datePublished\":\"2023-07-13T10:44:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/\"},\"wordCount\":929,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/new.societechimiquedefrance.fr\\\/wp-content\\\/uploads\\\/2026\\\/02\\\/JCJC-winenr-768x1024.jpg\",\"articleSection\":[\"Actualit\u00e9s\"],\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/\",\"url\":\"https:\\\/\\\/staging-scf.agence-nsw.xyz\\\/chemobiologie\\\/fr\\\/actualites\\\/prix-de-these\\\/\",\"name\":\"Prix de th\u00e8se - 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